Pathology

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The Department of Pathology provides reference laboratory support for Northwestern Ohio. Specialty services in anatomic pathology include cytopathology/fine needle aspiration service, neuropathology, hematopathology, surgical pathology, renal pathology, and ultrastructural pathology.

Services Offered

PGM

Blood Transfusion Services The laboratory is directed by a pathologist Board-Certified in Transfusion Medicine. The following services are provided by the laboratory: blood typing, blood group antibody identification, blood transfusion reaction work-up, serological studies for hemolytic disease of the newborn and medical consultation for topics related to transfusion medicine, including but not limited to blood transfusions indications, blood component therapy, and management of platelet alloimmunization.   Laboratory phone number:  (419) 383-5212; Medical Director (Bob Booth, MD) phone number:  (419) 383-3482.

Clinical Chemistry Clinical Chemistry is a fully automated laboratory which analyzes frequently ordered chemistry tests on blood, urine and other body fluids. Laboratory tests include electrolytes, intermediate metabolites, therapeutic drug monitoring, enzymes, lipids, carbohydrates and electrophoresis. The laboratory provides 24-hour service, including STAT and profile testing. Clinical consultation is available upon request.  Laboratory phone number:  (419) 383-7686; Medical Director (Amira Gohara, MD) phone number:  (419) 383-4918.

Molecular Diagnostics The Molecular Diagnostics Laboratory provides state of the art technology and molecular assays for the detection of human genetic diseases and infectious diseases.  Tests include CT/NG, HIV viral load, BK virus, 16S rRNA gene sequencing for identification of bacteria, rRNA gene sequencing for fungi and yeast, Factor II, Factor V, and MTHFR mutations.  The department has a Molecular Diagnostics Consult Service for physicians and clinicians who need advisement regarding available testing methods and indications as well as official interpretive reports evaluating laboratory data in the clinical context of individual patients.  Laboratory phone number:  (419) 383-5636. 

Clinical Microbiology The Clinical Microbiology Laboratory is state of the art and provides microbiology services in aerobic and anaerobic bacteriology, mycology, and molecular diagnostics of infectious diseases.  Other testing includes: cryptococcal antigen, bacterial vaginosis, enterohemorrhagic E. coli (0157:H7), Salmonella and Shigella sp., and Illumigene Clostridium difficile nucleic acid amplification test. The department has a Clinical Microbiology Consult Service where official consultative reports are provided by the medical director who has extensive experience and training in general microbiology, antibiotic susceptibility testing, and molecular infectious diseases. This service is available to physicians and clinicians who need advisement regarding available testing methods and indications as well as official interpretive reports evaluating laboratory data in the clinical context of individual patients.  Laboratory phone number:  (419) 383-6646. A requisition/ordering form can be found here.

Cytopathology We offer quality-oriented GYN (pap smears) and non-GYN cytology by a team of board-certified cytopathologists, state of the art Thin Prep® and SurePath® liquid-based cytology, as well as conventional pap smears. Fine needle aspiration is performed on palpable nodules, along with immediate adequacy assessment.  Consultation phone number:  (419) 383-3482.

We offer in-house screening of SurePath ®, Thin Prep ® and conventional pap smears with 2-4 day turn around time, correlation of pap smear with surgical pathology specimens to enhance patient care, and high risk Human Papillomavirus (HPV) DNA probe as requested or reflex tested.

In addition, the University of Toledo Laboratories is a full-service pathology lab providing a complete spectrum of clinical lab tests and surgical pathology services, including tissue biopsies, immunohistochemistry, tumor markers, autopsies, and consultations.

Fine Needle Aspiration Service:  Fine needle aspiration (FNA) involves the removal of a sample of cells, using a fine needle, from a suspicious mass for diagnostic purposes. This can be performed on an outpatient basis or at the patient’s bedside. They can be performed by clinicians or cytopathologists (if the lesion is palpable or with use of ultrasound), subspecialty clinicians (endoscopic ultrasound- guided lesions of the lung, stomach, duodenum or pancreas), or radiologists (ultrasound or CT-guided lesions). Consultation phone number:  (419) 383-3482.

Neuropathology: Dr. Robert Mrak is a Board-certified neuropathologist, who offers interpretation of brain tumor biopsies and surgical resections, interpretation of brain biopsies for non-neoplastic conditions, interpretation of nerve and muscle biopsies, and consultation for autopsy neuropathology. We offer competitive rates and convenient/flexible billing arrangements, as well as direct patient billing, computerized reporting (electronic signature) and direct auto-faxing capabilities, telephone consultation available with the neuropathologist. consultation phone number:  (419) 383-3469

Hematology & Clinical Microscopy Hematology is directed by a Board-Certified Hematopathologist, Robert Booth, M.D., and provides a generally complete list of routine and special tests for an accurate hematologic diagnosis. Leukemia diagnosis includes special cytochemical stains and coordination with Flow Cytometry and Electron Microscopy as necessary. Cytogenetics is recommended, but is a send out test. Bone marrow diagnostic consultations are welcome. Clinical Microscopy includes urine and fluid analysis.  Consultaton (Dr. Booth) phone number:  (419) 383-3482; hematology/urinalysis laboratory phone number:  (419) 383-5211 or (419) 383-7668.

Immunology The Division of Immunology has three sections: General Immunology offers diagnostic tests for infectious diseases, autoimmune diseases and immune deficiency diseases are performed, histocompatibility/transplant immunology lab where work up for transplant patients and cellular immunology tests are done, and flow cytometry lab where leukemia and lymphoma phenotyping, as well as DNA analysis of tumor assessment of the immune system of transplant and immune deficiency patients is performed.  Histocompatibility/transplant immunology laboratory phone number: (419) 383-4292.    Immunology Laboratory phone number:  (419) 383-4300.  Medical Director, division of Immunology (Amira Gohara, MD) phone number:  (419) 383-4918.

Surgical Pathology Laboratory diagnosis encompasses all kinds of biopsy and resected samples. Modern, up-to-date ancillary techniques are available - immunohistochemistry, flow cytometry, and electron microscopic analysis.  Consultations and laboratory phone number:  (419) 383-3482.  Medical Director (Luis De Las Casas, MD) phone number:  (419) 383-5033.

Ultrastructural Pathology The Division of Ultrastructural Pathology is a fully equipped laboratory for transmission electron microscopy with modern ancillary equipment and a new FEI Technai Spirit microscope. Diagnostic services that are available include diagnostic evaluation of kidney, muscle, nerve, and other biopsy material. In addition to routine ultrastructural techniques, we offer specialized immunocytochemical analysis of biopsy specimens (e.g., kidney, muscle, tumor) and specialized techniques for platelet analysis and virus identification. The laboratory is capable of diagnosing platelet dysfunction related to deficiency of dense granules by a technique called the platelet whole mount method. For most specimens, prompt fixation of small (1-2 mm) specimens in 3% buffered glutaraldehye is ideal. Ultrastructural analysis of specimens fixed with properly buffered formalin can also be done, if necessary. Special handling of specimens may be required for some samples; blood samples, for instance, must be collected in an acid dextrose citrate (ACD) vacutainer tube (10 cc preferred), kept at room temperature, and sent by overnight courier. For all diagnostic consultations, a clinical history is also required. Please call for additional instructions.  Consultations and laboratory phone number:  (419) 383-3484. 

Make an Appointment

419.383.5438

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  • Health Science Campus
  • UT Medical Center
  • 3065 Arlington Ave, Toledo, OH 43614, Rm 0136
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Last Updated: 7/29/14