Cardiovascular Research Studies
Study Title: The Treatment of Iliac and Femoral Atherosclerotic Lesions Using the Self-expanding Astron and Astron Pulsar Stents.
Study Purpose: The objective of this study is to separately demonstrate the safety and efficacy of BIOTRONIK's Astron and Astron Pulsar stents. The Astron Pulsar stent will be used for the treatment of femoro-popliteal lesions, located in the native superficial femoral artery (SFA) or proximal popliteal artery (PPA), while the Astron stent will be used for the treatment of the common or external iliac artery lesions.
Principal Investigator: Mark Burket, M.D.
Study Coordinator: Chris Eisenhauer, RN BSN, for more information, please contact 419.383.3853.
Study Title: Ablation Versus Anti-Arrhythmic (AA) Drug Therapy for AF - Pivotal Trial (CABANA)
Study Purpose: The CABANA Trial has the overall goal of establishing the appropriate roles for medical and ablative intervention for atrial fibrillation (AF). The CABANA Trial is designed to test the hypothesis that the treatment strategy of left atrial catheter ablation for the purpose of eliminating atrial fibrillation (AF) will be superior to current state-of-the-art therapy with either rate control or rhythm control drugs for reducing total mortality in patients with untreated or incompletely treated AF.
Principal Investigators: Jennifer Cummings, M.D. and Mohammed Y. Kanjwal, M.D.
Study Coordinator: Chris Eisenhauer, RN BSN, for more information, please contact 419.383.3853.
Study Title: Descending Thoracic Aortic Aneurysm Endovascular Repair Post-approval Study (THRIVE)
Study Purpose: The purpose of this study is to evaluate the long-term safety and effectiveness of the Talent Thoracic Stent Graft System for treatment of descending thoracic aneurysms (DTA)following U.S. market approval.
Principal Investigator: Munier Nazzal, M.D.
Study Coordinator: Olivia Twigg, for more information, please call 419-383-6810
Study Title: AngelMed for Early Recognition and Treatment of STEMI
Study Purpose: A prospective, randomized multicenter study of subjects with a high-risk of having a myocardial infarction (MI) due to acute coronary syndrome or bypass surgery.
Principal Investigator: Thomas Schwann, M.D.
Study Coordinator: Diane Anaya, for more information, please call 419-383-5150
Study Title: PROspective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE).
Study Purpose: A prospective multicenter imaging study for evaluation of chest pain. Objective is to determine whether an initial non-invasive anatomic imaging strategy with coronary CT angiography (CTA) will improve clinical outcomes in subjects with symptoms concerning for coronary artery disease relative to an initial functional testing strategy (usual care). Study hypothesis: initial anatomic testing strategy will provide information that will result in superior long-term health outcomes as compared to an initial functional testing strategy.
Principal Investigator: Jodi Tinkel, M.D.
Study Coordinator: Stephanie Marts, RN, for more information, please contact 419.383.3853
Study Title: Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Ularitide (Urodilatin) Intravenous Infusion in Patients Suffering From Acute Decompensated Heart Failure [TRUE-AHF].
Study Purpose: The purpose of this study is to evaluate the efficacy and safety of a continuous intravenous (IV) ularitide infusion on the clinical status and outcome of patients with acute decompensated heart failure (ADHF).
Principal Investigator: Samer Khouri, M.D.
Study Coordinator: Stephanie Marts, RN, for more information, please contact 419.383.3853.